GHRH
CJC-1295
CJC-1295 is a synthetic analog of growth-hormone-releasing hormone (GHRH). Unlike natural GHRH (which lasts only minutes in the bloodstream), the DAC version of CJC-1295 has a half-life of 7–8 days thanks to its covalent…
HPLC/MSCOAVerifiable serial≥99%
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▸ Overview
CJC-1295 is a synthetic analog of growth-hormone-releasing hormone (GHRH). Unlike natural GHRH (which lasts only minutes in the bloodstream), the DAC version of CJC-1295 has a half-life of 7–8 days thanks to its covalent binding to plasma albumin, producing a sustained, prolonged elevation of GH and IGF-1.
Category: GHRHPurity ≥99% HPLC/MS · COA per batch · Verifiable serial
▸ Mechanism of action
- Acts on GHRH-R receptors in the anterior pituitary, stimulating the synthesis and release of growth hormone (GH).
- Raises IGF-1 (insulin-like growth factor 1) levels in a sustained way, mediating most of its anabolic effects.
- Increases muscle protein synthesis, promotes lipolysis (fat burning) and inhibits hepatic gluconeogenesis.
- Improves bone mineral density by stimulating osteoblasts through the GH/IGF-1 axis.
- Enhances the recovery of connective tissue, cartilage and tendons by stimulating cell proliferation.
- Supports deep-sleep quality (stage III–IV), a key phase for natural GH secretion.
▸ Administration
- Subcutaneous route: injected with fine (insulin-type) needles in the abdomen or thigh.
- Reconstitution: supplied as a lyophilized powder; mixed with bacteriostatic water before use.
- Storage: the reconstituted vial must be refrigerated (2–8 °C) and used within 28 days.
▸ Timing
- Prior fasting: best applied with at least 2 hours of fasting so as not to interfere with GH pulses.
- Common schedules: before sleep (the main GH pulse occurs in deep sleep) or fasted in the morning.
- Post-injection: wait at least 30 minutes before eating foods rich in carbohydrates or fats.
▸ Dosing & cycles
- Frequency: generally 1–2 times per week (DAC version) or daily (non-DAC version).
- Cycles: usually 8–16 weeks with equivalent rest periods.
- The DAC version has an extended half-life (~8 days); the non-DAC (~30 min), so protocols differ.
▸ Combinations
- CJC-1295 + Ipamorelin: the classic GHRH/GHRP synergy that maximizes GH pulse amplitude.
- CJC-1295 + MK-677: combines pituitary stimulation with sustained oral GH secretion.
- CJC-1295 + AOD-9604: oriented toward body-composition research.
▸ Disclaimer
Use should be supervised by a healthcare professional. May cause fluid retention, numbness or redness at the injection site. Not suitable for human or veterinary use without prescription and medical supervision.
